A Comparative Study Between Recombinant Human Serum Albumin (rHSA) and Blood‑Derived Human Serum Albumin (HSA)

A Study on the Effects on Proliferation of Peripheral Blood Mononuclear Cells (PBMCs)

Test Cells: Human Peripheral Blood Mononuclear Cells (PBMCs)
Test System: Lymphocyte Expansion Medium

Conclusion:
1.The expansion efficacy of defatted recombinant human serum albumin (rHSA) is inferior to that of plasma‑derived human serum albumin (HSA).

2.Upon conjugation with specific fatty acids, rHSA shows better expansion efficacy than plasma‑derived human serum albumin (HSA).

Study on the Effects on Stem Cell Growth and Stemness Maintenance

Test Cells: Human Induced Pluripotent Stem Cells (iPSCs)
Test System: Pluripotent Stem Cell Expansion Medium

Conclusion:
1.The expansion performance of defatted recombinant human serum albumin (rHSA) is superior to that of plasma‑derived human serum albumin (HSA).
2.Cells cultured with plasma‑derived HSA show morphological changes and tend to undergo premature differentiation, while defatted rHSA contributes to stemness maintenance.

Important Notice